Preheat oven to 400°F. Use 1 tablespoon of the butter to grease the bottom and sides of a 9 x 13-inch baking dish. Set aside.
In a large bowl, toss the chopped pears with the Irish whiskey. Let the pears macerate for 30 minutes tossing a few times during that time.
To a separate bowl, add the oatmeal, almond flour, brown sugar, and cold cubed butter. Use your fingers to rub the mixture together until the grain resembles peas. Alternatively, you may add all to the barrel of a food processor and pulse until you reach the same consistency.
After the pears have macerated, drain about half of the liquid but not all. Add the honey, lemon juice, apple pie spice, cardamom, cinnamon, and vanilla bean seeds to the pears and toss well.
Turn the pear mixture out into the prepared baking dish evenly. Top evenly with the oatmeal and almond topping.
Bake for 35 to 45 minutes or until the top is sufficiently browned, you can smell the bake, and the fruit is bubbling up from beneath the crumble topping.
Pull from the oven and allow to sit on the counter until ready to serve. The crumble may be eaten warm or cool.