Casseroles – Southern Comfort in One Dish

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Embark on a flavorful adventure with our Southern-inspired casserole recipes, designed to bring warmth and comfort to your table. These dishes are steeped in tradition, featuring hearty ingredients like cheesy grits, cornbread, and rich layers of vegetables and meats. Perfect for family dinners, potlucks, or a cozy night in, these casseroles are not just meals but a celebration of Southern culinary heritage. Enjoy the ease of preparation and the joy of sharing these beloved recipes.

Chicken Spaghetti Casserole

A plate of creamy chicken spaghetti topped with cheese and herbs sits next to a green baking dish filled with more of the same spaghetti. A fork rests on the plate, and another fork is in the baking dish. A striped cloth is partially visible beneath the plate.
Image Credit: Culinary Hill

Chicken Spaghetti is a quintessential Southern comfort food that’s popular across various regions, especially in Texas. This dish combines tender spaghetti noodles, shredded chicken, and a creamy, cheesy sauce enhanced with seasoned tomatoes to add a kick. It’s revered for its comforting qualities making it a family dinner staple and a potluck gem!

Get the Recipe: Chicken Spaghetti Casserole

Southern-Style Macaroni & Cheese

A close-up view of a creamy, cheesy macaroni and cheese dish being scooped with a spoon. The macaroni is covered in melted cheese, showcasing a golden, bubbly, and slightly crispy texture on top.
Image Credit: South Your Mouth

My grandmother’s Southern Mac & Cheese recipe is prepared in the classic “custard-style,” using eggs and evaporated milk, and is baked until it reaches a golden, cheesy glory.

Get the Recipe: Southern-Style Macaroni & Cheese

Green Bean and Corn Casserole with Cheese

Scrumptious Green Bean and Corn Casserole with Cheese photo
Photo credit: The Cookie Rookie

Green Bean and Corn Casserole is a classic holiday side dish made with cheese, sour cream, and a cracker topping. Perfect for Thanksgiving!
Get the Recipe: Green Bean and Corn Casserole with Cheese

Mamaw’s Chicken & Rice Casserole

A close-up of a baked chicken and rice casserole in a glass dish. The dish contains chunks of cooked chicken and creamy rice, topped with a slightly browned and crispy layer of cheese. A serving spoon is partially dipped into the casserole.
Image Credit: Sweet Little Bluebird

Mamaw’s Chicken & Rice Casserole is a cherished recipe, celebrated for its simplicity, rich flavor, and comforting qualities. This classic dish is both easy to prepare and delicious, epitomizing old-school home cooking at its best. Get the Recipe: Mamaw’s Chicken & Rice Casserole

Best Southern Corn Pudding Casserole

A crock of steamed corn pudding with herbs.
Image Credit: Not Entirely Average

Bring a touch of Southern comfort to your BBQ with this corn pudding recipe, adding warmth and homely flavors to your grilled corn options. Its ease of preparation and comforting taste make it a fitting choice for transforming your summer BBQ spread.
Get the Recipe: Best Southern Corn Pudding

Old-Fashioned Tuna Casserole

A baked casserole dish filled with golden-brown noodles topped with breadcrumbs, placed on a wooden surface next to a blue and white checkered napkin.
Photo credit: The Cookin’ Chicks

Old-Fashioned Tuna Casserole offers a nostalgic taste of comfort with tender egg noodles, a creamy sauce, and crunchy onions. It’s a quick dinner solution that’s perfect for busy weeknights, providing plenty of leftovers for lunch the next day.
Get the Recipe: Old-Fashioned Tuna Casserole

Loaded Mashed Potato Casserole

A beautifully presented photo of Loaded Mashed Potato Casserole
Photo credit: The Cookie Rookie

Level up your side dish game with this delicious Loaded Mashed Potato Casserole. Creamy and rich and easy to make ahead of time.
Get the Recipe: Loaded Mashed Potato Casserole

Creamy Loaded Cauliflower Casserole

An oval-shaped casserole dish filled with a baked dish topped with melted cheese, chopped green onions, crispy bacon bits, and dollops of sour cream. A spoon rests in the dish, indicating it's ready to be served. A striped yellow napkin is nearby.
Creamy Loaded Cauliflower Casserole. Photo credit: Dr. Davinah’s Eats.

This Creamy Loaded Cauliflower Casserole is a low-carb delight, perfect for summer casseroles. With flavors like sour cream, cheese, green onions, and crispy bacon, it’s a delicious substitute for traditional loaded potatoes.
Get the Recipe: Creamy Loaded Cauliflower Casserole

Best Easy and Creamy Squash Casserole

A glass baking dish filled with baked squash casserole.
Photo credit: Not Entirely Average.

Easy Squash Casserole makes a delicious side dish to just about any main dish and is perfect for using up all of those zucchini and yellow squash still lingering in many gardens. This recipe gets brownie points for being a fantastic freezer casserole.
Get the Recipe: Best Easy and Creamy Squash Casserole

Chicken on the Ritz Casserole

A spoonful of chicken casserole with a Ritz cracker topping.
Photo credit: Not Entirely Average.

Rich and creamy ‘Chicken on The Ritz’ Casserole is made with just 9 ingredients and assembles in no time! This comforting dish is a busy-night savior, and if you’ve got a juicy rotisserie chicken on hand, you’re already halfway to a stress-free dinner victory!
Get the Recipe: Chicken on the Ritz Casserole

Hashbrown Casserole

A close-up of a spoon lifting a portion of cheesy hashbrown casserole with melted cheese, herbs, and a golden-brown crust. The casserole appears creamy and well-baked, with grated potatoes and melted cheese visible.
Image Credit: Will Cook for Smiles

This homemade cheesy hashbrown casserole offers a delightful side dish adored by many. It’s a comforting potato creation enriched with cheddar cheese and a creamy sauce, all crafted without canned soup and baked until it reaches gooey perfection.

Get the Recipe: Hashbrown Casserole

Asparagus Casserole

Asparagus Casserole
Photo credit: Erren’s Kitchen

You’re gonna adore our simple Asparagus Casserole recipe, great for any meal. It’s a cheesy, crunchy delight with a hint of elegance.
Get the Recipe: Asparagus Casserole

Sweet Potato Casserole

A beautifully presented photo of Sweet Potato Casserole
Photo credit: The Cookie Rookie

This easy Sweet Potato Casserole recipe is a classic holiday side dish. Marshmallows and pecans make for a great texture and flavor.
Get the Recipe: Sweet Potato Casserole

Vegan Broccoli Casserole

Vegan Broccoli Casserole
Photo credit: Namely Marly

You’ll love the cheesy flavor of this easy Vegan Broccoli Casserole infused with rice, broccoli, and cheese in every bite. Serve it straight from the skillet or transfer it to a baking dish and bake until golden brown around the edges. It’s a perfect side dish!
Get the Recipe: Vegan Broccoli Casserole

Southern Green Bean Casserole

A green bean casserole topped with crispy fried onions, with a wooden spoon partially submerged in the dish.
Photo credit: Blackberry Babe

Southern Green Bean Casserole is a household favorite, made special with the addition of stuffing mix. This dish brings together the comforting flavors of green beans and savory stuffing, making it a standout side for comforting dinners.
Get the Recipe: Southern Green Bean Casserole

Scalloped Corn Casserole with Ritz Crackers

Scalloped Corn Casserole With Ritz Crackers
Photo credit: Kitchen Divas

Use a buttery Ritz cracker topping for this creamy scalloped corn casserole recipe. This side dish is a favorite you’ll enjoy time and time again.
Get the Recipe: Scalloped Corn Casserole with Ritz Crackers

Turkey and Noodles Tetrazzini

A creamy turkey tetrazzini garnished with chopped herbs and topped with breadcrumbs, with a partially visible metal fork in the dish.
Photo credit: Not Entirely Average

Transform your leftover turkey into a culinary masterpiece with our easy-to-follow Turkey and Noodles Tetrazzini recipe! You can use the same magic to create a mouthwatering Chicken Tetrazzini with leftover rotisserie chicken, too. Either way, get ready to revolutionize your leftovers!
Get the Recipe: Turkey and Noodles Tetrazzini

Chicken Cauliflower Casserole

Chicken Cauliflower Casserole
Photo credit: The Honour System

Delight in this Cauliflower Chicken Casserole where tender chicken meets steamed cauliflower, embraced in a velvety sauce and crowned with gooey cheese. The harmonious blend of flavors crafts a cozy, fulfilling dish that is both nourishing and delectable.
Get the Recipe: Chicken Cauliflower Casserole

Southern Pineapple Casserole

A close-up view of a dessert featuring chunks of yellow pineapple coated in a glossy yellow gelatinous substance, topped with a crumbly, golden-brown crust. The dessert is presented in a glass dish.
Image Credit: The Country Cook

Pineapple Casserole is a beloved Southern staple made from a unique combination of pineapple, cheese, and crackers, making it an ideal complement to comfort meals and especially ham. This casserole may be unfamiliar if you’re not a Southerner, but its mix of flavors is likely to win over any newcomer!

Get the Recipe: Southern Pineapple Casserole

Beef Mushroom Country Casserole

Beef Mushroom Country Casserole
Photo credit: Budget Bytes

Beef & Mushroom Country Casserole is a filling and flavorful hot meal that the whole family will love, and with NO cream of soups!
Get the Recipe: Beef Mushroom Country Casserole

King Ranch Chicken Casserole

King Ranch Chicken Casserole
Photo credit: Budget Bytes

This made from scratch King Ranch Chicken Casserole has layers of chicken, tortillas, cheese, and a creamy sauce, with NO canned soups!
Get the Recipe: King Ranch Chicken Casserole

Easy Cheesy Beef and Bean Casserole

Easy Cheesy Beef And Bean Casserole
Photo credit: Cheerful Cook

This easy cheesy beef and bean casserole is perfect for a quick, tasty, and satisfying dinner. Perfect for busy weeknights.
Get the Recipe: Easy Cheesy Beef and Bean Casserole

Cajun Seafood Rice Casserole

Shrimp and rice in a skillet.
Photo credit: call Me PMc

Cajun Seafood Rice Casserole is packed with bold flavors and comforting warmth. It’s both spicy and filling.
Get the Recipe: Cajun Seafood Rice Casserole

Chicken and Waffle Casserole

Piece of chicken and waffle casserole on a plate.
Photo credit: Upstate Ramblings

Enjoy a twist on a classic favorite with Chicken and Waffle Casserole! With just 5 simple ingredients this breakfast casserole has an amazing balance of sweet & savory.
Get the Recipe: Chicken and Waffle Casserole

Butternut Squash Casserole

Close-up of a baked casserole dish with a wooden spoon scooping out a serving. The dish contains layers of creamy sauce, melted cheese, and a golden-brown breadcrumb topping with fresh sage leaves garnishing the surface.
Photo credit: The Cookie Rookie

This creamy and cozy Butternut Squash Casserole is so easy to make, and it checks off all the comforting side dish boxes for holiday feasts!
Get the Recipe: Butternut Squash Casserole

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About Jenny deRemer

I am a Charleston, South Carolina-based culinary novice, an ardent authority on all things travel, a designer by trade, and the creator of Not Entirely Average. I have a weakness for farmers' markets, delight in adventures way off the beaten path, enjoy documenting my many moods through photography, and have been known to conquer the occasional yard sale with gusto!

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